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Why do some medications need to be taken on an empty stomach? Some medicines need to be taken “before food” or “on an empty stomach “. This is because food and some drinks can affect the way these medicines work. For example, taking some medicines at the same time as eating may prevent your stomach and intestines absorbing the medicine, making it less effective.
What does empty stomach mean for medication? defines an empty stomach as “one hour before eating, or two hours after eating.” The F.D.A.’s two-hour rule is just a rule of thumb; the stomach will probably not be completely empty. The specific definition of an empty stomach varies from drug to drug.
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